Objective: Breast cancer is one of the most common cancers in women. Although breast cancer is a global health problem, its incidence has increased significantly in several Asian countries. High-risk populations according to epidemiological statistics can help to design interventions to reduce health inequalities. Therefore, this study was conducted to investigate the trend of breast cancer in Asia during 2010-2019.

Materials and Methods: We collected breast cancer data from the 2019 Global Burden of Disease (GBD) study from 2010 to 2019 in 49 Asian countries and territories. Annual case data and age-standardized rates (ASRs) were used to investigate the incidence, prevalence, mortality, and disability-adjusted life-years (DALYs) of breast cancer from 2010 to 2019 in 49 countries based on the socio-demographic index (SDI). Relative difference (%) between years was used to show the comparative changes in selected indicators’ age-standardized rates. Data were reported in values with a confidence interval (CI) of 95%.

Results: The results of the study show that age-standardized incidence rate (ASIR), age-standardized death rate (ASDR), age-standardized prevalence rate (ASPR), and DALYs ASR of breast cancer from 2010 to 2019 increased by 14, 5, 14, and 5%, respectively. Central Asia experienced a decreasing trend in ASDR and DALYs ASR. Only, High-income Asia Pacific experienced a decreasing trend in four indicators. Asian women aged 50 to 54 are most affected by breast cancer. Palestine experienced the highest ASIR and ASPR increasing trend among Asian countries, and Timor-Leste had the highest ASDR and DALYs ASR. United Arab Emirates experienced the highest ASIR and ASDR decreasing trend among Asian countries; Myanmar had the highest ASPR and DALYs ASR.

Conclusions: American and European countries are experiencing a decreasing trend in the ASIR, ASDR, and DALYs ASR caused by breast cancer, while in Asia only High-income Asia Pacific and Central Asia countries are witnessing a decreasing trend. Breast cancer is a threat to the health of many women in high and middle-SDI Asian countries. Breast cancer control measures such as screening programs, early diagnosis, and correcting modifiable risk factors are recommended to be designed and implemented based on the epidemiology and available resources of each country.