Objective: Chemotherapy results in side-effects that adversely affect patients’ quality of life. Nurses can reduce the side effects of chemotherapy and improve the quality of life by training patients. The study was conducted to determine the effect of individual training on patients with hematologic cancer on the quality of life and reduction of chemotherapy symptoms.

Patients and Methods: The study which was designed as a randomized controlled trial in pretest-posttest pattern.  The study includes 60 patients (30 patients each in intervention and control group). Data was collected with a questionnaire, EORTC QLQ C-30 Scale and Rotterdam Symptom Checklist. The intervention group was given individual training on side effects of chemotherapy.

Results: It was determined that the QOL levels of intervention group were higher than the control group. Chemotherapy symptoms, and Rotterdam symptoms were found to be higher in the patients of the intervention group.

Conclusions: The individual training gave positive results to the QOL and reduced side effects of chemotherapy. Nurses can improve patients’ QOL and reduce the side effects of chemotherapy by training.